Before you move to production it is strongly recommended that you first develop and test your application in test/development mode.
UPS has now removed the requiment for certification. You no longer need to certify to print regular/return labels.
FedEx still requires a certification process. To certify login to the FedEx Developer Center and request to be moved to production. They will email you with certification instructions. Usually, they just want to see a few sample GIF labels and the XML used to generate it.
You can access this information in the debug info. See the debug section in Troubleshooting.